Generation of biologically contained Ebola viruses
نویسندگان
چکیده
منابع مشابه
Generation of biologically contained Ebola viruses.
Ebola virus (EBOV), a public health concern in Africa and a potential biological weapon, is classified as a biosafety level-4 agent because of its high mortality rate and the lack of approved vaccines and antivirals. Basic research into the mechanisms of EBOV pathogenicity and the development of effective countermeasures are restricted by the current biosafety classification of EBOVs. We theref...
متن کاملMarburg and Ebola viruses
PRINTED FROM OXFORD MEDICINE ONLINE (www.oxfordmedicine.com). (c) Oxford University Press, 2014. All Rights Reserved. Under the terms of the l icence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Medicine Online for personal use (for details see Privacy Policy).date: 14 October 2014 Publisher: Oxford University Press Print Publication Date: Jul 2011 ...
متن کاملEbola and Marburg Viruses —
Ebolaand marburgviruses are members of the family Filoviridae. The filoviruses have caught the attention of the general public because of the gruesome hemorrhagic fever outbreaks they have caused in human populations in Africa. Recently, biodefense experts have begun to focus on them due to revelations put forth by defectors from the former Soviet bioweapons development programs. According to t...
متن کاملMarburg and Ebola viruses as aerosol threats.
Ebola and Marburg viruses are the sole members of the genus Filovirus in the family Filoviridae. There has been considerable media attention and fear generated by outbreaks of filoviruses because they can cause a severe viral hemorrhagic fever (VHF) syndrome that has a rapid onset and high mortality. Although they are not naturally transmitted by aerosol, they are highly infectious as respirabl...
متن کاملDisease modeling for Ebola and Marburg viruses.
The filoviruses Ebola and Marburg are zoonotic agents that are classified as both biosafety level 4 and category A list pathogens. These viruses are pathogenic in humans and cause isolated infections or epidemics of viral hemorrhagic fever, mainly in Central Africa. Their natural reservoir has not been definitely identified, but certain species of African bat have been associated with Ebola and...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2008
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.0708057105